Surgical Conversion for Initially Unresectable Locally Advanced Hepatocellular Carcinoma: case series

Abstract

Conversion therapy has been established as a strategy that combines chemotherapy and additional surgical resection for the treatment of live cancer with unresectable metastases. Patients with potentially resectable or even unresectable advanced hepatocellular carcinoma (HCC) can undergo radical surgical resection after conversion therapy, and the postoperative treatment effect is good. Here we reported 4 cases of unresectable HCC who underwent radical surgical resection after conversion therapy. We also performed literature review of conversion therapy for HCC. We found that success rate of conversion therapy for patients with advanced HCC was low. Most of the patients with successful conversion therapy were patients younger than 60 years old. We need explore better strategies of conversion therapy for clinical treatment of liver cancer.